Skip to content
HCN Grants Est. 2026
No. RFA-RM-27-014 · National Institutes of Health
Open

Validation Center for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) (U54 Clinical Trials Not Allowed)

Dealbreakers Cost share: not stated Audit: not stated Reimbursement-only: not stated

At a glance

No plain-language summary yet for this grant — the official description below is the best source.

What it funds

  • Health
  • Research & Discovery
  • Patients & People with Health Conditions
  • Researchers & Scholars
  • AI, Computing & Cybersecurity
  • Biomedical & Disease Research
  • Health Care Delivery, Access & Workforce
Official description from grants.gov

The NIH Common Fund, with other NIH Institutes and Centers (ICs), intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for the Precision Medicine with Artificial Intelligence - Integrating Imaging with Multimodal Data (PRIMED-AI) program, which seeks to develop innovative, reliable, and cost-effective AI-based tools that integrate clinical imaging with other health data types to enhance personalized medicine for patients with chronic and other health conditions. The program’s Validation Center initiative will serve as an independent hub for third party verification, validation, and uncertainty quantification of AI-enabled, image-based, multimodal Clinical Decision Support (CDS) tools through the systematic retesting and harmonization of PRIMED-AI deliverables to comprehensively characterize performance of the CDS tools. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the U54 activity code. Investigators with expertise and insights into the validation of CDS tools and the confidence bounds and potential failure modes of AI predictions are encouraged to begin to consider applying for this new NOFO.

Who can apply

  • County governments
  • For-profit organizations other than small businesses
  • Independent school districts
  • Native American tribal governments (Federally recognized)
  • Native American tribal organizations (other than Federally recognized)
  • Nonprofits with 501(c)(3) status (other than higher education)
  • Private institutions of higher education
  • Public and State controlled institutions of higher education
  • Public housing authorities / Indian housing authorities
  • Small businesses
Geographic restriction None found in the announcement — likely nationwide

Change history

  1. Jul 11, 2026 Title updated
  2. Jul 11, 2026 Status: forecasted → open
  3. Jul 11, 2026 Deadline set: Oct 2, 2026