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HCN Grants Est. 2026
No. PAR-24-329 · National Institutes of Health
Open

Development and Testing of Novel Interventions to Improve HIV Prevention, Treatment, and Program Implementation for People Who Use Substances (R34 Clinical Trial Required)

Dealbreakers No cost share required Audit: not stated
Not reimbursement-only
“Grant: A financial assistance mechanism providing money, property, or both to an eligible entity to carry out an approved project or activity.” — From the announcement

At a glance

This program funds pilot or feasibility studies of new or adapted interventions to prevent HIV infection, improve HIV care, or reduce barriers and expand delivery of proven HIV prevention or care interventions for people who use substances. It is for clinical trial applications and does not support projects focused only on manuals, protocols, or standardization of protocols. Nonprofit organizations, universities, governments, for-profit organizations, tribal entities, faith-based or community-based organizations, and foreign organizations are eligible to apply. Applicants may request up to $450,000 in direct costs over 3 years, with no more than $225,000 in direct costs in any one year, and no cost sharing is required.

AI-generated summary — verify against the announcement

What it funds

  • Education
  • Health
  • Research & Discovery
  • Patients & People with Health Conditions
  • Biomedical & Disease Research
  • Public Health, Prevention & Nutrition
  • Substance Use & Addiction
Official description from grants.gov

This notice of funding opportunity (NOFO) encourages formative research, intervention development, and pilot-testing of interventions. Primary scientific areas of focus include the feasibility, tolerability, acceptability and safety of novel or adapted interventions that target HIV prevention, treatment or services research for people who use drugs. For the purposes of this NOFO, "intervention" may include behavioral, social, or structural approaches, as well as combination biomedical and behavioral approaches that prevent the acquisition and transmission of HIV infection, or improve clinical outcomes for persons living with HIV.

Who can apply

  • City or township governments
  • County governments
  • For-profit organizations other than small businesses
  • Independent school districts
  • Native American tribal governments (Federally recognized)
  • Native American tribal organizations (other than Federally recognized)
  • Nonprofits with 501(c)(3) status (other than higher education)
  • Nonprofits without 501(c)(3) status (other than higher education)
  • Others
  • Private institutions of higher education
  • Public and State controlled institutions of higher education
  • Public housing authorities / Indian housing authorities
  • Small businesses
  • Special district governments
  • State governments
Geographic restriction None found in the announcement — likely nationwide