At a glance
This grant supports planning studies needed to complete the protocol for a future multi-center Phase II or later cancer prevention or control clinical trial. Applicants may be nonprofits, universities, governments, for-profits, small businesses, tribal organizations, faith-based or community organizations, and foreign organizations, and the award is for up to three years. Budgets are limited to $225,000 per year, with up to $450,000 in direct costs over three years if no pilot/feasibility trial is included, or up to $600,000 if a pilot/feasibility clinical trial is included. No cost sharing is required. Applications must address topics within the mission of the NIH cancer prevention and control divisions, and first-in-human studies, purely mechanistic or animal studies, and applications without preliminary efficacy or effectiveness data are not responsive.
What it funds
Official description from grants.gov
The purpose of this FOA is to facilitate well planned clinical trials across the cancer prevention and control spectrum aimed at improving prevention/ interception, cancer-related health behaviors, screening, early detection, healthcare delivery, management of treatment-related symptoms, supportive care, and the long-term outcomes of cancer survivors. Although the scientific literature or preliminary data may provide the rationale for conducting a clinical trial, investigators often lack critical information about the study population, accrual challenges, intervention, outcome/ endpoints, data/statistical challenges or operational risks necessary to finalize the trial protocol completely. These information gaps can result in multiple protocol changes before and after trial start-up, leading to the need for additional time and expenses that may prevent study completion. Further, the suitability and feasibility of new trial designs, which minimize infrastructure and reduce costs may need to be tested in the context of a particular intervention, at-risk group, symptom or venue. Preparatory studies may fill information gaps and address unknowns, improving trial design and knowledge of trial feasibility and thus saving NCI time and money.
Who can apply
- City or township governments
- County governments
- For-profit organizations other than small businesses
- Independent school districts
- Native American tribal governments (Federally recognized)
- Native American tribal organizations (other than Federally recognized)
- Nonprofits with 501(c)(3) status (other than higher education)
- Nonprofits without 501(c)(3) status (other than higher education)
- Others
- Private institutions of higher education
- Public and State controlled institutions of higher education
- Public housing authorities / Indian housing authorities
- Small businesses
- Special district governments
- State governments