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Simpler Grants

No. PAR-24-268 · National Institutes of Health

Open

Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program (UC2- Clinical Trial Not Allowed)

grants.gov listing Full announcement (NOFO)
Dealbreakers No cost share required Audit: not stated
Not reimbursement-only
“Funding Instrument Cooperative Agreement: A financial assistance mechanism used when there will be substantial Federal scientific or programmatic involvement.” — From the announcement
Award range
Up to $500,000
Expected awards
Not specified
Application deadline
Jan 27, 2027
Posted
Oct 30, 2024
Last verified
6 days ago

At a glance

AI summary

This program supports resource-limited institutions in building biomedical research capacity, improving the research environment, and strengthening sponsored programs administration. Applicants must be eligible U.S. higher education institutions or nonprofits that meet the notice’s resource-limited institution definition; foreign organizations and foreign components are not eligible. Applications must propose work in at least two funding areas, and may include multiple participating organizations if all are eligible; partner organizations may help but do not receive development funding. Direct costs may not exceed $500,000 per year, the project period can be up to five years, there is no cost share, and clinical trials are not allowed.

AI-generated summary — verify against the announcement

What it funds

  • Education
  • Health
  • Capacity Building & Technical Assistance
  • Research & Discovery
  • Researchers & Scholars
  • Biomedical & Disease Research
  • Higher Education Access, Institutions & Humanities
  • Research Infrastructure, Instrumentation & Data
Official description from grants.gov

The Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program aims to promote broad participation in the biomedical research ecosystem by supporting resource limited organizations to conduct research, enhance the research environment, and increase sponsored programs administration capacity.This program intends to support eligible, domestic organizations with limited research resources and few biomedical doctoral students.

Who can apply

  • Nonprofits with 501(c)(3) status (other than higher education)
  • Nonprofits without 501(c)(3) status (other than higher education)
  • Others
  • Private institutions of higher education
  • Public and State controlled institutions of higher education
Geographic restriction None found in the announcement — likely nationwide
Set-aside Set aside or prioritized for: HBCU; Tribal college (TCU)
“Historically Black College or University (HBCU) (see 20 U.S.C. 1061(2)), OR Tribal entity defined as: A federally recognized AI/AN Tribe, as defined under 25 U.S.C. 1603(14); or A Tribal college or university, a Tribal health program, or a Tribal organization as defined under 25 U.S.C. 1603 (24), (25), and (26), respectively; or A consortium of two or more of those Tribal entities.” — From the announcement

Program history

USASpending.gov

Assistance listing 93.121 · Oral Diseases and Disorders Research

Real awards this federal program has made — the whole assistance listing (93.121), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 155 $429,000 $306,500 – $571,863
FY 2025 277 $429,000 $310,295 – $829,259
FY 2024 301 $491,193 $310,985 – $1,283,003
FY 2023 320 $444,000 $298,673 – $1,756,575
FY 2022 295 — —
FY 2021 305 — —

For comparison, this notice advertises Up to $500,000.

Dollar figures are based on the 1,000 most recent awards we store, not all 1,653 — award counts are complete.

Who wins it Higher education (1,224), Nonprofit (242), Business (71) of 1,653 awards — categories can overlap.
Top states CA (124) · PA (83) · MA (82) · NY (70) · TX (35)
Largest recent awards
  1. TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE $6,128,166 · FY 2023
  2. THE GENERAL HOSPITAL CORPORATION $4,961,133 · FY 2023
  3. RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK $4,002,156 · FY 2023
  4. DANA-FARBER CANCER INSTITUTE, INC. $3,742,682 · FY 2025
  5. TRUSTEES OF INDIANA UNIVERSITY $3,736,064 · FY 2023

Source: USASpending.gov · refreshed Aug 16, 2026

Assistance listing 93.213 · Research and Training in Complementary and Integrative Health

Real awards this federal program has made — the whole assistance listing (93.213), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 58 $441,813 $190,230 – $676,906
FY 2025 51 $472,500 $321,065 – $1,329,943
FY 2024 100 $562,397 $286,558 – $1,285,052
FY 2023 92 $695,557 $380,313 – $1,709,004
FY 2022 94 $715,153 $419,983 – $1,985,928
FY 2021 92 $1,686,420 $625,217 – $3,082,386

For comparison, this notice advertises Up to $500,000.

Who wins it Higher education (342), Nonprofit (97), Business (33) of 487 awards — categories can overlap.
Top states CA (77) · MA (59) · NY (29) · NC (12) · IL (11)
Largest recent awards
  1. REGENTS OF THE UNIVERSITY OF MINNESOTA $21,646,919 · FY 2022
  2. UNIVERSITY OF FLORIDA $11,192,369 · FY 2022
  3. DUKE UNIVERSITY $7,025,837 · FY 2022
  4. THE RAND CORPORATION $6,237,409 · FY 2023
  5. THE SPAULDING REHABILITATION HOSPITAL CORPORATION $5,991,655 · FY 2023

Source: USASpending.gov · refreshed Aug 21, 2026

Assistance listing 93.242 · Mental Health Research Grants

Real awards this federal program has made — the whole assistance listing (93.242), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 685 $450,175 $166,962 – $799,127
FY 2025 600 $987,843 $427,193 – $1,695,032
FY 2024 883 — —
FY 2023 898 — —
FY 2022 987 — —
FY 2021 945 — —

For comparison, this notice advertises Up to $500,000.

Dollar figures are based on the 1,000 most recent awards we store, not all 4,998 — award counts are complete.

Who wins it Higher education (3,666), Nonprofit (858), Business (222) of 4,998 awards — categories can overlap.
Top states CA (175) · NY (134) · MA (106) · PA (85) · TX (31)
Largest recent awards
  1. THE REGENTS OF THE UNIVERSITY OF COLORADO $24,765,147 · FY 2025
  2. MASSACHUSETTS INSTITUTE OF TECHNOLOGY $21,714,815 · FY 2025
  3. OHIO STATE UNIVERSITY, THE $19,515,757 · FY 2025
  4. ALBERT EINSTEIN COLLEGE OF MEDICINE $18,270,924 · FY 2025
  5. DUKE UNIVERSITY $15,039,330 · FY 2025

Source: USASpending.gov · refreshed Sep 5, 2026

Assistance listing 93.273 · Alcohol Research Programs

Real awards this federal program has made — the whole assistance listing (93.273), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 184 $402,938 $173,631 – $648,788
FY 2025 175 $497,661 $311,150 – $1,290,396
FY 2024 238 $456,041 $156,782 – $1,152,589
FY 2023 328 $667,361 $350,624 – $1,893,194
FY 2022 314 $1,716,398 $413,174 – $2,854,878
FY 2021 274 — —

For comparison, this notice advertises Up to $500,000.

Dollar figures are based on the 1,000 most recent awards we store, not all 1,513 — award counts are complete.

Who wins it Higher education (1,164), Nonprofit (201), Business (79) of 1,513 awards — categories can overlap.
Top states CA (111) · NC (65) · NY (56) · PA (44) · MA (23)
Largest recent awards
  1. THE JOHNS HOPKINS UNIVERSITY $49,287,017 · FY 2022
  2. THE GENERAL HOSPITAL CORPORATION $17,455,711 · FY 2023
  3. REGENTS OF THE UNIVERSITY OF MINNESOTA $12,536,957 · FY 2023
  4. UNIVERSITY OF CALIFORNIA, SAN DIEGO $12,114,859 · FY 2024
  5. THE LELAND STANFORD JUNIOR UNIVERSITY $6,476,031 · FY 2025

Source: USASpending.gov · refreshed Sep 5, 2026

Assistance listing 93.279 · Drug Use and Addiction Research Programs

Real awards this federal program has made — the whole assistance listing (93.279), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 428 $422,523 $183,034 – $700,682
FY 2025 588 $709,054 $348,214 – $1,489,059
FY 2024 714 — —
FY 2023 724 — —
FY 2022 740 — —
FY 2021 606 — —

For comparison, this notice advertises Up to $500,000.

Dollar figures are based on the 1,000 most recent awards we store, not all 3,800 — award counts are complete.

Who wins it Higher education (2,743), Nonprofit (534), Business (366) of 3,800 awards — categories can overlap.
Top states CA (130) · MA (90) · NY (86) · PA (72) · MD (56)
Largest recent awards
  1. FLORIDA INTERNATIONAL UNIVERSITY $7,372,834 · FY 2025
  2. BETH ISRAEL DEACONESS MEDICAL CENTER, INC. $7,081,684 · FY 2025
  3. UNIVERSITY OF WASHINGTON $7,003,822 · FY 2025
  4. REACX PHARMACEUTICALS, INC. $6,900,000 · FY 2025
  5. WORCESTER POLYTECHNIC INSTITUTE $6,889,914 · FY 2025

Source: USASpending.gov · refreshed Aug 18, 2026

Assistance listing 93.310 · Trans-NIH Research Support

Real awards this federal program has made — the whole assistance listing (93.310), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 115 $582,838 $418,649 – $860,735
FY 2025 401 $786,876 $385,000 – $1,467,198
FY 2024 455 $1,174,898 $558,715 – $2,057,532
FY 2023 643 $1,437,358 $1,200,000 – $2,578,153
FY 2022 666 — —
FY 2021 689 — —

For comparison, this notice advertises Up to $500,000.

Dollar figures are based on the 1,000 most recent awards we store, not all 2,969 — award counts are complete.

Who wins it Higher education (2,212), Nonprofit (582), Business (34) of 2,969 awards — categories can overlap.
Top states CA (153) · MA (103) · NY (93) · PA (63) · MI (21)
Largest recent awards
  1. THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK $34,424,926 · FY 2023
  2. THE GENERAL HOSPITAL CORPORATION $33,014,143 · FY 2023
  3. MAYO CLINIC JACKSONVILLE (A NONPROFIT CORPORATION) $17,574,818 · FY 2024
  4. TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE $16,308,508 · FY 2025
  5. UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC. $14,064,599 · FY 2025

Source: USASpending.gov · refreshed Aug 18, 2026

Assistance listing 93.846 · Arthritis, Musculoskeletal and Skin Diseases Research

Real awards this federal program has made — the whole assistance listing (93.846), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 148 $377,506 $124,696 – $576,799
FY 2025 274 $432,326 $224,620 – $1,053,137
FY 2024 357 $473,099 $306,518 – $1,364,153
FY 2023 400 $611,188 $300,000 – $1,870,687
FY 2022 420 — —
FY 2021 357 — —

For comparison, this notice advertises Up to $500,000.

Dollar figures are based on the 1,000 most recent awards we store, not all 1,956 — award counts are complete.

Who wins it Higher education (1,364), Nonprofit (386), Business (144) of 1,956 awards — categories can overlap.
Top states CA (115) · MA (97) · NY (92) · PA (78) · NC (52)
Largest recent awards
  1. WAKE FOREST UNIVERSITY $10,449,074 · FY 2023
  2. THE GENERAL HOSPITAL CORPORATION $5,795,791 · FY 2023
  3. REGENTS OF THE UNIVERSITY OF MICHIGAN $3,579,362 · FY 2023
  4. VANDERBILT UNIVERSITY MEDICAL CENTER $3,213,591 · FY 2026
  5. UNIVERSITY OF ALABAMA AT BIRMINGHAM $3,106,910 · FY 2023

Source: USASpending.gov · refreshed Aug 23, 2026

Assistance listing 93.853 · Extramural Research Programs in the Neurosciences and Neurological Disorders

Real awards this federal program has made — the whole assistance listing (93.853), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 654 $405,461 $120,825 – $587,738
FY 2025 923 $491,085 $157,949 – $1,077,840
FY 2024 1,031 — —
FY 2023 1,194 — —
FY 2022 1,228 — —
FY 2021 1,132 — —

For comparison, this notice advertises Up to $500,000.

Dollar figures are based on the 1,000 most recent awards we store, not all 6,162 — award counts are complete.

Who wins it Higher education (4,669), Nonprofit (990), Business (259) of 6,162 awards — categories can overlap.
Top states CA (153) · NY (99) · MA (93) · PA (74) · TX (39)
Largest recent awards
  1. THE LELAND STANFORD JUNIOR UNIVERSITY $5,747,701 · FY 2025
  2. YALE UNIV $4,888,497 · FY 2025
  3. MAYO CLINIC $3,746,535 · FY 2026
  4. REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE $3,153,019 · FY 2025
  5. UNIVERSITY OF CALIFORNIA, LOS ANGELES $3,109,857 · FY 2025

Source: USASpending.gov · refreshed Aug 23, 2026

Assistance listing 93.859 · Biomedical Research and Research Training

Real awards this federal program has made — the whole assistance listing (93.859), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 1,048 $420,000 $325,870 – $487,506
FY 2025 1,115 — —
FY 2024 1,171 — —
FY 2023 1,383 — —
FY 2022 1,574 — —
FY 2021 1,321 — —

For comparison, this notice advertises Up to $500,000.

Dollar figures are based on the 1,000 most recent awards we store, not all 7,612 — award counts are complete.

Who wins it Higher education (6,024), Nonprofit (734), Business (565) of 7,612 awards — categories can overlap.
Top states CA (149) · NY (81) · TX (73) · PA (60) · MA (55)
Largest recent awards
  1. UNIVERSITY OF MISSISSIPPI MEDICAL CENTER $5,185,402 · FY 2026
  2. UNIVERSITY OF WISCONSIN SYSTEM $3,654,310 · FY 2026
  3. THE TRUSTEES OF PRINCETON UNIVERSITY $2,993,000 · FY 2026
  4. BATTELLE MEMORIAL INSTITUTE $2,843,142 · FY 2026
  5. UNIVERSITY OF LOUISVILLE $2,652,150 · FY 2026

Source: USASpending.gov · refreshed Aug 23, 2026

Assistance listing 93.866 · Aging Research

Real awards this federal program has made — the whole assistance listing (93.866), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 795 $493,972 $248,999 – $713,195
FY 2025 1,033 $643,089 $467,538 – $1,733,010
FY 2024 1,560 — —
FY 2023 1,539 — —
FY 2022 1,715 — —
FY 2021 1,595 — —

For comparison, this notice advertises Up to $500,000.

Dollar figures are based on the 1,000 most recent awards we store, not all 8,237 — award counts are complete.

Who wins it Higher education (6,015), Nonprofit (1,370), Business (538) of 8,237 awards — categories can overlap.
Top states CA (153) · NY (110) · MA (100) · TX (57) · PA (41)
Largest recent awards
  1. REGENTS OF THE UNIVERSITY OF MICHIGAN $15,345,206 · FY 2026
  2. UNIVERSITY OF UTAH $10,793,501 · FY 2025
  3. THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK $10,223,348 · FY 2026
  4. SUTTER BAY HOSPITALS $9,466,491 · FY 2025
  5. TUFTS MEDICAL CENTER PARENT, INC. $8,296,115 · FY 2026

Source: USASpending.gov · refreshed Aug 23, 2026

Assistance listing 93.867 · Vision Research

Real awards this federal program has made — the whole assistance listing (93.867), not just this notice.

Fiscal year Awards Median award Middle half
FY 2026 (so far) 189 $440,263 $132,837 – $633,742
FY 2025 309 $464,903 $260,661 – $1,026,742
FY 2024 408 $630,967 $342,920 – $1,431,708
FY 2023 401 $771,099 $422,359 – $1,867,311
FY 2022 391 — —
FY 2021 394 — —

For comparison, this notice advertises Up to $500,000.

Dollar figures are based on the 1,000 most recent awards we store, not all 2,092 — award counts are complete.

Who wins it Higher education (1,564), Nonprofit (300), Business (168) of 2,092 awards — categories can overlap.
Top states CA (182) · NY (96) · MA (90) · MD (48) · TX (48)
Largest recent awards
  1. REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE $5,256,090 · FY 2023
  2. OHIO STATE UNIVERSITY, THE $4,539,043 · FY 2025
  3. ALLEN INSTITUTE $4,260,011 · FY 2025
  4. THE GENERAL HOSPITAL CORPORATION $4,026,010 · FY 2024
  5. UNIVERSITY OF CALIFORNIA SANTA CRUZ $3,712,398 · FY 2025

Source: USASpending.gov · refreshed Aug 23, 2026