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HCN Grants Est. 2026
No. PA-25-163 · National Institutes of Health
Open

Alcohol Treatment, Pharmacotherapy, and Recovery Research (R01 Clinical Trial Required)

Dealbreakers No cost share required Audit: not stated
Not reimbursement-only
“Funding Instrument Grant: A financial assistance mechanism providing money, property, or both to an eligible entity to carry out an approved project or activity.” — From the announcement

At a glance

This program funds human clinical trial research on alcohol use disorder treatment and recovery, including medications, behavioral therapies, recovery processes, translational research, digital methods, and studies focused on special-emphasis populations such as people with health disparities, psychiatric comorbidity, women, adolescents and young adults, and older adults. Eligible applicants include U.S. and non-U.S. organizations, including nonprofits, universities, for-profits, governments, tribal entities, faith-based and community-based organizations, and foreign organizations. The award is a grant, new and resubmission applications are allowed, direct costs may not exceed $500,000 without prior approval, the project period can be up to five years, and no cost sharing is required. Applications that focus on brief intervention dissemination, prevention, community settings, preclinical animal studies, polysubstance use, HIV/AIDS-related studies, organ-associated diseases, basic experimental studies involving humans, or nonclinical trials will not be considered responsive.

AI-generated summary — verify against the announcement

What it funds

  • Health
  • Research & Discovery
  • Patients & People with Health Conditions
  • Substance Use & Addiction
Official description from grants.gov

The National Institute on Alcohol Abuse and Alcoholism solicits applications for an R01 Clinical Trial Required mechanism focusing on alcohol treatment and recovery research. This NOFO will focus broadly on topics relevant for treatment of and recovery from alcohol use disorder (AUD), including: medications development, precision medicine, behavioral therapies and mechanisms of behavioral change (MOBC), recovery, translational research, and innovative methods and technologies for AUD treatment and recovery.

Who can apply

  • City or township governments
  • County governments
  • For-profit organizations other than small businesses
  • Independent school districts
  • Native American tribal governments (Federally recognized)
  • Native American tribal organizations (other than Federally recognized)
  • Nonprofits with 501(c)(3) status (other than higher education)
  • Nonprofits without 501(c)(3) status (other than higher education)
  • Others
  • Private institutions of higher education
  • Public and State controlled institutions of higher education
  • Public housing authorities / Indian housing authorities
  • Small businesses
  • Special district governments
  • State governments
Geographic restriction None found in the announcement — likely nationwide