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HCN Grants Est. 2026
No. PAR-25-167 · National Institutes of Health
Open

Cancer Prevention and Control Clinical Trials Grant Program (R01 Clinical Trial Required)

Dealbreakers No cost share required Audit: not stated
Not reimbursement-only
“Grant: A financial assistance mechanism providing money, property, or both to an eligible entity to carry out an approved project or activity.” — From the announcement

At a glance

This grant program funds investigator-initiated clinical trials in cancer prevention and control that may improve early detection, screening, prevention, healthcare delivery, quality of life, or survivorship. It does not support trials for cancer diagnosis or cancer treatment, and Phase III support is limited to public health, healthcare delivery, and related psychosocial, behavioral, environmental, policy, health system, or implementation interventions. A wide range of organizations may apply, including nonprofits, schools, governments, for-profits, tribal organizations, faith-based and community-based organizations, and foreign organizations or foreign components of U.S. organizations. Awards are for up to 5 years, the number of awards is not set in advance, application budgets are not limited but must fit the project, and no cost sharing is required.

AI-generated summary — verify against the announcement

What it funds

  • Education
  • Health
  • Research & Discovery
  • Patients & People with Health Conditions
  • Biomedical & Disease Research
  • Health Care Delivery, Access & Workforce
  • Public Health, Prevention & Nutrition
Official description from grants.gov

Through this notice of funding opportunity (NOFO), the National Cancer Institute (NCI) invites applications for support of investigator-initiated clinical trials that have the potential to reduce the burden of cancer through improvements in early detection, screening, prevention and interception, healthcare delivery, quality of life, and/or survivorship related to cancer; with such attributes, the proposed studies should also have the potential to improve clinical practice and/or public health. Applications submitted to this NOFO must include studies that meet the National Institutes of Health (NIH) definition of a clinical trial (see NOT-OD-15-015 for details) and provide specific clinical trial information as described in this FOA. This NOFO does not and will not support clinical trials for studies of cancer diagnosis and/or oncologic therapy in patients. The proposed investigator-initiated projects should be related to the programmatic interests of the NCI Division of Cancer Prevention and/or the NCI Division of Cancer Control and Population Sciences.

Who can apply

  • City or township governments
  • County governments
  • For-profit organizations other than small businesses
  • Independent school districts
  • Native American tribal governments (Federally recognized)
  • Native American tribal organizations (other than Federally recognized)
  • Nonprofits with 501(c)(3) status (other than higher education)
  • Nonprofits without 501(c)(3) status (other than higher education)
  • Others
  • Private institutions of higher education
  • Public and State controlled institutions of higher education
  • Public housing authorities / Indian housing authorities
  • Small businesses
  • Special district governments
  • State governments
Geographic restriction None found in the announcement — likely nationwide