At a glance
This program funds short, one-year R03 research projects that collect preliminary data on understudied proteins linked to pain and pain management, including work such as pilot studies, assay development, model development, biomarker validation, and early target discovery. Only applications focused on the listed eligible proteins are responsive, and clinical trials and clinical drug development studies are not allowed. Eligible applicants include many types of U.S. institutions and organizations, including nonprofits, universities, governments, small businesses, and foreign organizations are not eligible. Awards are limited to $100,000 in direct costs for one year, the number of awards is not set, and no cost sharing is required. Foreign components in U.S. applications are allowed.
What it funds
Official description from grants.gov
The purpose of this notice of funding opportunity (NOFO) is to solicit applications for pilot projects to identify new druggable targets for pain within the understudied druggable proteome. Awards will support generation of preliminary data and/or tools around eligible understudied protein(s) listed in this NOFO. This NOFO is intended to jumpstart research on understudied proteins within the context of pain and pain management and provide applicants with sufficient funding to perform basic biochemical and/or biological work to further the characterization of understudied proteins to identify new druggable targets for pain. This NOFO is part of the NIH Helping to End Addiction Long Term (HEAL) initiative to accelerate the development of novel medications to treat all aspects of the opioid addiction cycle, including progression to chronic use, withdrawal symptoms, craving, relapse, and overdose.
Who can apply
- City or township governments
- County governments
- For-profit organizations other than small businesses
- Independent school districts
- Native American tribal governments (Federally recognized)
- Native American tribal organizations (other than Federally recognized)
- Nonprofits with 501(c)(3) status (other than higher education)
- Nonprofits without 501(c)(3) status (other than higher education)
- Others
- Private institutions of higher education
- Public and State controlled institutions of higher education
- Public housing authorities / Indian housing authorities
- Small businesses
- Special district governments
- State governments