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HCN Grants Est. 2026
No. PAR-25-346 · National Institutes of Health
Open

Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21 Clinical Trial Not Allowed)

Dealbreakers No cost share required Audit: not stated
Not reimbursement-only
“Grant: A financial assistance mechanism providing money, property, or both to an eligible entity to carry out an approved project or activity.” — From the announcement

At a glance

This grant funds exploratory bioengineering research to test new capabilities or improvements for basic biomedical, pre-clinical, or clinical research, clinical care delivery, or accessibility. It uses the NIH R21 grant mechanism and does not allow clinical trials. Eligible applicants include U.S. and non-U.S. organizations such as universities, nonprofits, for-profits, governments, tribes, and foreign organizations, and foreign components of U.S. organizations are allowed. The total direct cost budget for the two-year project period may not exceed $275,000, with no more than $200,000 in any single year, and the program did not state a required cost share. The number of awards depends on NIH appropriations and the quality of applications.

AI-generated summary — verify against the announcement

What it funds

  • Education
  • Health
  • Technology & Product Development
  • Researchers & Scholars
  • Biomedical & Disease Research
Official description from grants.gov

Through this engineering-oriented Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) intends to encourage submissions of exploratory/developmental Bioengineering Research Grant (EBRG) applications to demonstrate feasibility and potential utility of new capabilities or improvements in quality, speed, efficacy, operability, costs, and/or accessibility of solutions to problems in basic biomedical, pre-clinical, or clinical research, clinical care delivery, or accessibility.

Who can apply

  • City or township governments
  • County governments
  • For-profit organizations other than small businesses
  • Independent school districts
  • Native American tribal governments (Federally recognized)
  • Native American tribal organizations (other than Federally recognized)
  • Nonprofits with 501(c)(3) status (other than higher education)
  • Nonprofits without 501(c)(3) status (other than higher education)
  • Others
  • Private institutions of higher education
  • Public and State controlled institutions of higher education
  • Public housing authorities / Indian housing authorities
  • Small businesses
  • Special district governments
  • State governments
Geographic restriction None found in the announcement — likely nationwide