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HCN Grants Est. 2026
No. PAR-25-143 · National Institutes of Health
Open

Dissemination and Implementation Research in Health (R21 Clinical Trial Optional)

Dealbreakers No cost share required Audit: not stated
Not reimbursement-only
“Grant: A financial assistance mechanism providing money, property, or both to an eligible entity to carry out an approved project or activity.” — From the announcement

At a glance

This NOFO funds research on how to better disseminate, implement, sustain, scale up, spread, or de-implement evidence-based health interventions, practices, programs, tools, treatments, guidelines, and policies. It also supports work to advance dissemination and implementation research methods and measures, using an R21 exploratory/developmental award. Applications must fit the mission of at least one participating NIH Institute or Center, and some institute sections highlight topic areas such as cancer, genomics, aging, and infectious disease. The text does not state the award size, number of awards, cost-share requirements, or any geographic restrictions.

AI-generated summary — verify against the announcement

What it funds

  • Education
  • Environment
  • Health
  • Income Security and Social Services
  • Research & Discovery
  • Researchers & Scholars
  • Biomedical & Disease Research
  • Health Care Delivery, Access & Workforce
Official description from grants.gov

The purpose of this Funding Opportunity Announcement (FOA) is to support studies that will identify, develop, and/or test strategies for overcoming barriers to the adoption, adaptation, integration, scale-up, and sustainability of evidence-based interventions, practices, programs, tools, treatments, guidelines, and policies. Conversely, there is a benefit in understanding circumstances that create a need to stop or reduce (de-implement) the use of practices that are ineffective, unproven, low-value, or harmful. In addition, studies to advance dissemination and implementation research methods and measures are encouraged.All applications must be within the scope of the mission of one of the Institutes/Centers listed above.

Who can apply

  • City or township governments
  • County governments
  • For-profit organizations other than small businesses
  • Independent school districts
  • Native American tribal governments (Federally recognized)
  • Native American tribal organizations (other than Federally recognized)
  • Nonprofits with 501(c)(3) status (other than higher education)
  • Nonprofits without 501(c)(3) status (other than higher education)
  • Others
  • Private institutions of higher education
  • Public and State controlled institutions of higher education
  • Public housing authorities / Indian housing authorities
  • Small businesses
  • Special district governments
  • State governments
Geographic restriction None found in the announcement — likely nationwide