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HCN Grants Est. 2026
No. PA-24-194 · National Institutes of Health
Open

NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)

Dealbreakers No cost share required Audit: not stated
Not reimbursement-only
“Indirect costs will be reimbursed at 8% of modified total direct costs.” — From the announcement

At a glance

This NIH program funds postdoctoral researchers who are moving toward independent, tenure-track or equivalent faculty positions. It does not allow applicants to propose their own clinical trials, though they may gain experience in a mentor-led trial. Applicants must be in mentored postdoctoral training, have no more than 4 years of postdoctoral research experience, and have a clinical or research doctorate; foreign organizations and non-U.S. components of U.S. organizations are not eligible. The award can last up to 5 years total, with up to 2 years for the mentored K99 phase and up to 3 years for the independent R00 phase, and NIH says the number of awards depends on appropriations and meritorious applications. Cost sharing is not required; for the R00 phase, total costs may not exceed $249,000 per year, and the extramural K99 phase has 8% indirect costs on modified total direct costs.

AI-generated summary — verify against the announcement

What it funds

  • Education
  • Environment
  • Food and Nutrition
  • Health
  • Income Security and Social Services
  • Research & Discovery
  • Training, Fellowship & Career Development
  • Researchers & Scholars
  • Biomedical & Disease Research
Official description from grants.gov

The purpose of the NIH Pathway to Independence Award (K99/R00) program is to increase and maintain a strong cohort of new and talented, NIH-supported, independent investigators. This program is designed to facilitate a timely transition of outstanding postdoctoral researchers with a research and/or clinical doctorate degree from mentored, postdoctoral research positions to independent, tenure-track or equivalent faculty positions. The program will provide independent NIH research support during this transition in order to help awardees to launch competitive, independent research careers.

Who can apply

  • City or township governments
  • County governments
  • For-profit organizations other than small businesses
  • Independent school districts
  • Native American tribal governments (Federally recognized)
  • Native American tribal organizations (other than Federally recognized)
  • Nonprofits with 501(c)(3) status (other than higher education)
  • Nonprofits without 501(c)(3) status (other than higher education)
  • Others
  • Private institutions of higher education
  • Public and State controlled institutions of higher education
  • Public housing authorities / Indian housing authorities
  • Small businesses
  • Special district governments
  • State governments
Geographic restriction None found in the announcement — likely nationwide