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HCN Grants Est. 2026
No. PAS-25-205 · National Institutes of Health
Open

Stimulating Hematology Investigation: New Endeavors (SHINE) (R01 Clinical Trial Not Allowed)

Dealbreakers No cost share required Audit: not stated
Not reimbursement-only
“Grant: A financial assistance mechanism providing money, property, or both to an eligible entity to carry out an approved project or activity.” — From the announcement

At a glance

This program supports innovative hematology research in areas related to NIDDK, NIA, or NHLBI missions, with a focus on basic and early translational studies. It is for investigator-initiated R01 applications that do not propose clinical trials. Eligible applicants include universities, nonprofits, for-profit organizations, governments, tribal entities, faith-based or community-based organizations, regional organizations, and foreign organizations are not eligible; foreign components of U.S. applications are allowed. NIH expects about 5–8 awards totaling $2.5 million in FY 2025, budgets are not capped but must fit the project, the project period may be up to 5 years, and no cost sharing is required.

AI-generated summary — verify against the announcement

What it funds

  • Food and Nutrition
  • Health
  • Research & Discovery
  • Researchers & Scholars
  • Biomedical & Disease Research
Official description from grants.gov

The Stimulating Hematology Investigation: New Endeavors (SHINE) program is intended to promote innovative, high-quality nonmalignant hematology research relevant to the missions of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institute of Aging (NIA), and the National Heart, Lung, and Blood Institute (NHLBI). Investigator-initiated research project grant applications (R01s) in specific areas of basic and early translational hematology research are invited to this program that supports growth in the nonmalignant hematology research domain. Specific emerging topics that are at the leading edge of the field will change over time and will be updated annually through the NIH Guide to Grants and Contracts and hyperlinked to this NOFO.

Who can apply

  • City or township governments
  • County governments
  • For-profit organizations other than small businesses
  • Independent school districts
  • Native American tribal governments (Federally recognized)
  • Native American tribal organizations (other than Federally recognized)
  • Nonprofits with 501(c)(3) status (other than higher education)
  • Nonprofits without 501(c)(3) status (other than higher education)
  • Others
  • Private institutions of higher education
  • Public and State controlled institutions of higher education
  • Public housing authorities / Indian housing authorities
  • Small businesses
  • Special district governments
  • State governments
Geographic restriction None found in the announcement — likely nationwide