Skip to content
HCN Grants Est. 2026
No. PAR-25-244 · National Institutes of Health
Open

Basic Research in Cancer Health Disparities (R21 Clinical Trial Not Allowed)

Dealbreakers No cost share required Audit: not stated
Not reimbursement-only
“Funding Instrument Grant: A financial assistance mechanism providing money, property, or both to an eligible entity to carry out an approved project or activity.” — From the announcement

At a glance

This program funds basic research on the biological and genetic causes and mechanisms of cancer health disparities, including pilot and feasibility studies, new methods and models, and secondary data analyses. Eligible applicants include a wide range of U.S. and non-U.S. organizations, including nonprofits, universities, governments, faith-based and community-based organizations, and foreign organizations. The grant does not allow clinical trials, does not require cost sharing, and awards may request up to $275,000 in direct costs over two years, with no more than $200,000 in any single year. Applications must focus on cancer health disparities tied to race, ethnicity, ancestry, or other underserved populations; studies of age or sex disparities alone, or behavioral, social, environmental, or community studies without biological mechanisms, are not responsive.

AI-generated summary — verify against the announcement

What it funds

  • Education
  • Health
  • Research & Discovery
  • Researchers & Scholars
  • Biomedical & Disease Research
Official description from grants.gov

This Notice of Funding Opportunity (NOFO) encourages grant applications from investigators interested in conducting basic, mechanistic research into the biological/genetic causes of cancer health disparities. These research project grants will support innovative studies designed to investigate biological/genetic bases of cancer health disparities, such as (1) mechanistic studies of biological factors associated with cancer health disparities, including those related to basic research in cancer biology or cancer prevention strategies, (2) the development and testing of new methodologies and models, and (3) secondary data analyses. This NOFO is also designed to aid and facilitate the growth of a nationwide cohort of scientists with a high level of basic research expertise in cancer health disparities research who can expand available resources and tools, such as biospecimens, patient derived models, and methods that are necessary to conduct basic research in cancer health disparities.

Who can apply

  • City or township governments
  • County governments
  • For-profit organizations other than small businesses
  • Independent school districts
  • Native American tribal governments (Federally recognized)
  • Native American tribal organizations (other than Federally recognized)
  • Nonprofits with 501(c)(3) status (other than higher education)
  • Nonprofits without 501(c)(3) status (other than higher education)
  • Others
  • Private institutions of higher education
  • Public and State controlled institutions of higher education
  • Public housing authorities / Indian housing authorities
  • Small businesses
  • Special district governments
  • State governments
Geographic restriction None found in the announcement — likely nationwide