Skip to content
HCN Grants Est. 2026
No. PAR-25-193 · National Institutes of Health
Open

Alcohol Treatment, Pharmacotherapy, and Recovery Research (R34 Clinical Trial required)

Dealbreakers No cost share required Audit: not stated
Not reimbursement-only
“Grant: A financial assistance mechanism providing money, property, or both to an eligible entity to carry out an approved project or activity.” — From the announcement

At a glance

This program funds human clinical trials related to alcohol use disorder treatment and recovery, including medications, behavioral therapies, translational research, digital tools, and studies focused on special-emphasis populations. It uses the R34 grant mechanism for planning and pilot work, such as building research teams, finalizing protocols, and collecting feasibility data for later studies. Applications may come from a wide range of U.S. and non-U.S. organizations, and foreign organizations and foreign components of U.S. organizations are allowed. Direct costs are limited to $450,000 over up to 3 years, with no more than $225,000 in direct costs in any single year, and the number of awards depends on appropriations and meritorious applications.

AI-generated summary — verify against the announcement

What it funds

  • Health
  • Research & Discovery
  • Low-Income & Underserved Communities
  • Patients & People with Health Conditions
  • Health Care Delivery, Access & Workforce
  • Public Health, Prevention & Nutrition
  • Substance Use & Addiction
Official description from grants.gov

The National Institute on Alcohol Abuse and Alcoholism solicits applications for an R34 Clinical Trial Optional mechanism focusing on alcohol health services. This NOFO will broadly focus on closing the treatment gap for individuals with alcohol use disorder (AUD); within this focus, there are five major areas of emphasis: (1) increasing access to treatment for AUD, (2) making treatment for AUD more appealing, (3) examining cost structures and insurance systems, (4) conducting studies on dissemination and implementation of existing evidence-based approaches to treating AUD, and (5) reducing health disparities as a means of addressing the treatment gap in AUD for health disparity populations.

Who can apply

  • City or township governments
  • County governments
  • For-profit organizations other than small businesses
  • Independent school districts
  • Native American tribal governments (Federally recognized)
  • Native American tribal organizations (other than Federally recognized)
  • Nonprofits with 501(c)(3) status (other than higher education)
  • Nonprofits without 501(c)(3) status (other than higher education)
  • Others
  • Private institutions of higher education
  • Public and State controlled institutions of higher education
  • Public housing authorities / Indian housing authorities
  • Small businesses
  • Special district governments
  • State governments
Geographic restriction None found in the announcement — likely nationwide